Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 5/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453607 | 1.00 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL24478917 | 0.77 | NPC1 (0.48) | SMN1; SMN2LMNAPOLBGAAMAPT | |
| SCHEMBL27453122 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27453022 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27453121 | 0.77 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27451894 | 0.75 | LMNA (0.48) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27451126 | 0.75 | MGLL (0.57) | KMT2AMEN1SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL27452949 | 0.74 | SMN1; SMN2 (0.47) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27453517 | 0.74 | LMNA (0.48) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27453518 | 0.73 | RAB9A (0.43) | KMT2AMEN1SMN1; SMN2POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |