SCHEMBL27456161

SCHEMBL27456161

Fc1cccc(Br)c1C(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11045185 0.83 TSHR (0.35)
SCHEMBL30266772 0.79 CES2 (0.36) CES2CES1HTT
SCHEMBL2268624 0.79 CES2 (0.36) CES2CES1HTT
SCHEMBL12986654 0.77 CES2 (0.35) CES2CES1HTT
SCHEMBL7181065 0.74 GAA (0.44) CES2CES1HTT
SCHEMBL20558458 0.74 MAOA (0.35) CES2CES1HTT
SCHEMBL6745071 0.74 CES2 (0.41) CES2CES1HTT
SCHEMBL29184015 0.73 CES2 (0.39) CES2CES1
SCHEMBL28773713 0.73 ALDH1A1 (0.32)
SCHEMBL31039433 0.72 CES2 (0.32) CES2CES1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103044181-A Method for preparing octene-1 by ethylene tetramerization reaction PETROCHINA CO LTD 2013-04-17 CN disclosed
CN-1651142-A Catalyst component used for ethylene oligomerization, preparing process and application thereof DAQING PETROCHEMICAL BRANCH CO (CN) 2005-08-10 CN disclosed
CN-1108193-C Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2003-05-14 CN disclosed
CN-1256968-A Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2000-06-21 CN disclosed