Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | SORD | Q00796 | 4/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704996 | 0.81 | CKS1B (0.55) | ALDH1A1KDM4ETSHRSMN1; SMN2SORD | |
| SCHEMBL21880062 | 0.79 | KMO (0.53) | ALDH1A1SORDGBA1 | |
| SCHEMBL31706098 | 0.78 | CKS1B (0.55) | MAP4K4ALDH1A1KDM4ESMN1; SMN2SORD | |
| SCHEMBL31705707 | 0.77 | SORD (0.42) | SORDGBA1 | |
| SCHEMBL27457780 | 0.76 | PTGER4 (0.45) | SORD | |
| SCHEMBL31705458 | 0.75 | CKS1B (0.44) | ALDH1A1KDM4ESMN1; SMN2TRPV1SORD | |
| SCHEMBL4546626 | 0.74 | ALDH1A1 (0.74) | ALDH1A1KDM4EADRB2TSHRSMN1; SMN2 | |
| SCHEMBL1911516 | 0.71 | SLC6A7 (0.53) | MAP4K4SMOALDH1A1KDM4EADRB2 | |
| SCHEMBL4197090 | 0.71 | HRH3 (0.46) | SORD | |
| SCHEMBL23972267 | 0.70 | PANK3 (0.60) | MAP4K4SMOALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |