SCHEMBL5667352

SCHEMBL5667352

O=C(O)c1cccc(-c2cccc(C(=O)O)c2C#Cc2ccccc2)c1C#Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 2/20 0.50
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 4/20 0.46
ALOX15 P16050 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
MYC P01106 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
APP P05067 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTPN11 Q06124 2/20 0.43
PTPRC P08575 1/20 0.43
PTPN2 P17706 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN6 P29350 1/20 0.43
PTPN9 P43378 1/20 0.43
DUSP3 P51452 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1713009 0.90 HNF4A (0.55) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL5668837 0.80 HNF4A (0.49) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL5667269 0.80 NR4A1 (0.49) HNF4ANPC1RAB9AALDH1A1ALOX15
Diphenylacetylene SCHEMBL7168945 0.79 HNF4A (0.56) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL5669586 0.78 HNF4A (0.44) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL5669133 0.77 HNF4A (0.50) HNF4AAKR1C2AKR1C1PTPN11PTPRC
SCHEMBL7149446 0.76 NPC1 (0.59) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL2745848 0.76 MMP2 (0.43) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL2256468 0.75 NPC1 (0.72) HNF4ANPC1RAB9AALDH1A1ALOX15
SCHEMBL29479413 0.75 NPC1 (0.72) HNF4ANPC1RAB9AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed