Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Tryptophan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL28338052 | 0.91 | KDM4E (0.55) | KISS1RERAP2 | |
| Dl-Tryptophan SCHEMBL28838628 | 0.91 | IL1RN (0.48) | KISS1RIL1RNERAP2OPRM1OPRD1 | |
| Dl-Tryptophan SCHEMBL28250969 | 0.90 | KDM4E (0.54) | — | |
| Dl-Tryptophan SCHEMBL27780062 | 0.90 | TUBB4A (0.48) | NPBWR1KISS1R | |
| Dl-Tryptophan SCHEMBL27458897 | 0.90 | TUBB4A (0.48) | NPBWR1KISS1R | |
| Tryptophan SCHEMBL29220361 | 0.90 | KISS1R (0.47) | NPBWR1KISS1R | |
| Dl-Tryptophan SCHEMBL29076836 | 0.89 | KMT2A (0.58) | KISS1RIL1RNERAP2OPRM1OPRD1 | |
| Dl-Tryptophan SCHEMBL27641172 | 0.88 | IL23R (0.50) | — | |
| Dl-Tryptophan SCHEMBL19924290 | 0.88 | KDM4E (0.50) | NPBWR1 | |
| Tryptophan SCHEMBL28205930 | 0.88 | KDM4E (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116804041-A | Polypeptide for detecting residual quantity and activity of various proteases and application thereof | 重庆艾美迪生物科技有限公司 | 2023-09-26 | — | — | CN | disclosed |