Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466266 | 0.96 | — | — | |
| Water SCHEMBL28775675 | 0.96 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1CA1CA2 | |
| Water SCHEMBL27258720 | 0.96 | — | — | |
| Water SCHEMBL27635361 | 0.96 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL1508492 | 0.96 | — | — | |
| Water SCHEMBL27498654 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Water SCHEMBL28785521 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Fluoride SCHEMBL27484078 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Water SCHEMBL27590704 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Water SCHEMBL27972222 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103351463-B | Polycarbonate resin, polycarbonate resin composition, optical film, and polycarbonate resin molded article | MITSUBISHI CHEMICAL CORP. (JP) | 2016-01-06 | — | — | CN | disclosed |
| CN-104017199-A | Polycarbonate and method for producing same | MITSUBISHI CHEM CORP | 2014-09-03 | — | — | CN | disclosed |
| CN-103992469-A | Polycarbonate and molded article thereof | MITSUBISHI CHEM CORP | 2014-08-20 | — | — | CN | disclosed |
| CN-101896535-B | Method for producing polycarbonate | MITSUBISHI CHEM CORP | 2014-07-09 | — | — | CN | disclosed |
| CN-103865248-A | Polycarbonate resin composition and molded article | MITSUBISHI CHEM CORP | 2014-06-18 | — | — | CN | disclosed |
| CN-102656231-B | Polycarbonate resin composition, and molded body, film, plate and injection molded article obtained by molding same | MITSUBISHI CHEM CORP | 2014-04-30 | — | — | CN | disclosed |
| CN-103351463-A | Polycarbonate resin, polycarbonate resin composition, optical film, and polycarbonate resin molded article | MITSUBISHI CHEM CORP | 2013-10-16 | — | — | CN | disclosed |
| CN-102224182-B | Polycarbonate resin, polycarbonate resin composition, optical film, and polycarbonate resin molded article | MITSUBISHI CHEM CORP | 2013-08-07 | — | — | CN | disclosed |
| CN-101896536-B | Method for producing polycarbonate and molded polycarbonate article | MITSUBISHI CHEM CORP | 2013-01-02 | — | — | CN | disclosed |
| CN-102816322-A | Method for producing polycarbonate and molded polycarbonate article | MITSUBISHI CHEM CORP | 2012-12-12 | — | — | CN | disclosed |
| CN-1564837-B | Aromatic polycarbonate, process for producing the same, polycarbonate composition, and hollow container obtained from the composition | MITSUBISHI CHEM CORP | 2010-05-26 | — | — | CN | disclosed |
| CN-101585914-A | Aromatic polycarbonate, process for producing the same, polycarbonate composition, and hollow container obtained from the composition | MITSUBISHI CHEM CORP (JP) | 2009-11-25 | — | — | CN | disclosed |
| CN-1261483-C | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 2006-06-28 | — | — | CN | disclosed |
| CN-1564837-A | Aromatic polycarbonate, process for producing the same, polycarbonate composition, and hollow container obtained from the composition | MITSUBISHI CHEM CORP (JP) | 2005-01-12 | — | — | CN | disclosed |
| CN-1174021-C | Process for producing aromatic polycarbonate | ������������ʽ���� | 2004-11-03 | — | — | CN | disclosed |
| CN-1158328-C | Process for producing polycarbonate resin | 帝人株式会社 | 2004-07-21 | — | — | CN | disclosed |
| CN-1466605-A | Process for producing aromatic polycarbonate | 三菱化学株式会社 | 2004-01-07 | — | — | CN | disclosed |
| CN-1426432-A | Method for producing aromatic polycarbonate | TEIJIN LTD (JP) | 2003-06-25 | — | — | CN | disclosed |
| CN-1392884-A | Process for producing aromatic polycarbonate and method for storing raw materials | TEIJIN LTD (JP) | 2003-01-22 | — | — | CN | disclosed |
| CN-1242386-A | Process for producing polycarbonate resin | TEIJIN LTD (JP) | 2000-01-26 | — | — | CN | disclosed |