⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584974 | 0.77 | APP (0.40) | — | |
| SCHEMBL27675673 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL27650969 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL2776293 | 0.69 | KDM4E (0.32) | — | |
| SCHEMBL7356480 | 0.69 | CCR5 (0.31) | — | |
| SCHEMBL27483584 | 0.68 | PPARA (0.36) | — | |
| SCHEMBL2079127 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL8106329 | 0.67 | THRA (0.39) | — | |
| SCHEMBL3209325 | 0.66 | APP (0.40) | — | |
| SCHEMBL27606308 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152864-C | Phenylphenanthridines with PDE-IV inhibiting activity | ��̹��ҽҩ��˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1336919-A | Phenylphenanthridines with PDE-IV inhibiting activity | BYK GULDEN LOMBERG CHEM FAB (DE) | 2002-02-20 | — | — | CN | disclosed |