SCHEMBL27464004

SCHEMBL27464004

O=C(Cl)c1ccc2c(c1)C(=O)N(Cl)C2=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
KMT2A Q03164 3/20 0.47
HPGD P15428 2/20 0.45
MEN1 O00255 2/20 0.45
ENPP2 Q13822 1/20 0.44
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
MAPT P10636 1/20 0.40
LMNA P02545 1/20 0.40
APEX1 P27695 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4853822 0.83 ALDH1A1 (0.53) POLBKMT2AHPGDMEN1ALDH1A1
SCHEMBL14544423 0.80 POLB (0.44) POLBKMT2AHPGDMEN1ENPP2
SCHEMBL1994560 0.80 CA9 (0.57) POLBKMT2AMEN1ALDH1A1MAPT
SCHEMBL13417772 0.79 POLB (0.73) POLBKMT2AHPGDMEN1ENPP2
SCHEMBL1618166 0.78 ESR1 (0.61) POLBKMT2AMEN1ALDH1A1MAPT
SCHEMBL12710955 0.78 POLB (0.43) POLBKMT2AHPGDMEN1ENPP2
SCHEMBL5667639 0.77 PTPRC (0.47) POLBKMT2AHPGDMEN1ALDH1A1
SCHEMBL6925901 0.77 PTPRC (0.47) POLBKMT2AHPGDMEN1ALDH1A1
SCHEMBL1995596 0.76 S100B (0.57) POLBKMT2AMEN1ALDH1A1TDP1
SCHEMBL28399814 0.75 TTR (0.59) KMT2AHPGDMEN1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1138818-C Polyamideimide for optical communications and method for preparing the same 三星电子株式会社 2004-02-18 CN disclosed
CN-1226571-A Polyamideimide for optical communications and method for preparing the same SAMSUNG ELECTRONICS CO LTD (KR) 1999-08-25 CN disclosed