Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27465660 | 0.87 | SLC6A3 (0.40) | SLC6A3LMNA | |
| SCHEMBL27467641 | 0.79 | ALDH1A1 (0.32) | SLC6A3LMNA | |
| SCHEMBL27482390 | 0.70 | PTGS1 (0.35) | PTGS1PTGS2 | |
| SCHEMBL27465661 | 0.70 | KCNH2 (0.43) | SLC6A3LMNA | |
| SCHEMBL27483479 | 0.69 | PTGS1 (0.35) | PTGS1PTGS2 | |
| SCHEMBL27523626 | 0.69 | KMT2A (0.45) | SLC6A3LMNA | |
| SCHEMBL27466731 | 0.67 | HDAC8 (0.40) | SLC6A3 | |
| SCHEMBL15219463 | 0.63 | SHBG (0.40) | — | |
| SCHEMBL4766116 | 0.62 | POLB (0.44) | SLC6A3LMNA | |
| SCHEMBL8257649 | 0.62 | KDM4E (0.36) | PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |