Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467640 | 0.87 | PTGS1 (0.35) | SLC6A3LMNA | |
| SCHEMBL27465661 | 0.79 | KCNH2 (0.43) | SLC6A3LMNASLC6A2SLC6A4ALOX5 | |
| SCHEMBL27523626 | 0.76 | KMT2A (0.45) | SLC6A3LMNA | |
| SCHEMBL27515306 | 0.74 | FFAR1 (0.45) | SLC6A3SLC6A2SLC6A4METAP2 | |
| SCHEMBL27552958 | 0.74 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4METAP2 | |
| SCHEMBL27482051 | 0.71 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27466230 | 0.70 | APP (0.42) | SLC6A3SLC6A2SLC6A4METAP2 | |
| SCHEMBL27467641 | 0.70 | ALDH1A1 (0.32) | SLC6A3LMNA | |
| SCHEMBL27466733 | 0.67 | HDAC8 (0.38) | SLC6A3SLC6A4 | |
| SCHEMBL21985594 | 0.62 | LMNA (0.39) | SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |