Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550633 | 0.77 | LMNA (0.39) | KCNA5CYP3A4CYP2C19CYP2D6LMNA | |
| SCHEMBL27761462 | 0.74 | TAAR1 (0.36) | KCNH2TSHRKMT2AMEN1 | |
| SCHEMBL2008433 | 0.71 | RORC (0.42) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL27980202 | 0.70 | LMNA (0.39) | KCNA5CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL6850127 | 0.69 | RORC (0.46) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL28336538 | 0.69 | ALDH1A1 (0.48) | KCNA5CYP3A4CYP2C19LMNAALDH1A1 | |
| SCHEMBL5134393 | 0.68 | OPRM1 (0.46) | CYP2C19HTTLMNAALDH1A1KMT2A | |
| SCHEMBL12508295 | 0.68 | KCNA5 (0.71) | KCNA5CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL27515730 | 0.68 | POLB (0.43) | KCNA5CYP3A4CYP2C19NPSR1LMNA | |
| SCHEMBL12613218 | 0.67 | ALDH1A1 (0.42) | HTTNPSR1LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162450-C | New type phosphine oxide light initiation system and light colour solidifiable composition | �������⻯ѧƷ�ع�����˾ | 2004-08-18 | — | — | CN | disclosed |
| CN-1304940-A | New type phosphine oxide light initiation system and light colour solidifiable composition | CIBA SC HOLDING AG (CH) | 2001-07-25 | — | — | CN | disclosed |