Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618781 | 0.86 | MYC (0.50) | KDM4EALDH1A1HSD11B1CA1CA2 | |
| SCHEMBL27471073 | 0.79 | BCAT2 (0.42) | ALDH1A1CA1CA2CA9CA5A | |
| SCHEMBL3641319 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD11B1SLC1A3SLC1A2 | |
| Acetamide SCHEMBL539092 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1HSD11B1SLC1A3SLC1A2 | |
| SCHEMBL8799814 | 0.74 | MAPK13 (0.44) | ALDH1A1MYCCYP2C9HPGDKMT2A | |
| SCHEMBL8966630 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9GAA | |
| SCHEMBL11744143 | 0.74 | CD44 (0.50) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL475089 | 0.74 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD11B1GAACYP2C9 | |
| SCHEMBL29468592 | 0.74 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD11B1GAACYP2C9 | |
| SCHEMBL7707773 | 0.73 | G6PD (0.57) | ALDH1A1CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522937-C | Anthranilic acid amides, method for the production thereof, their use as antiarrhythmia agents, and pharmaceutical preparations thereof | AVENTIS PHARMA GMBH (DE) | 2009-08-05 | — | — | CN | disclosed |
| CN-1522244-A | Anthranilic acid amides, method for the production thereof, their use as antiarrhythmia agents, and pharmaceutical preparations thereof | ������ҽҩ�¹�����˾ | 2004-08-18 | — | — | CN | disclosed |