Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916169 | 0.74 | AKR1B1 (0.50) | TBXAS1TDP1PTGS2KMT2A | |
| SCHEMBL4398478 | 0.72 | KDM4E (0.46) | FFAR4ALOX15L3MBTL1PTGS2KMT2A | |
| SCHEMBL16542334 | 0.72 | FFAR4 (0.40) | FFAR4ALOX15L3MBTL1 | |
| SCHEMBL13886094 | 0.72 | TAAR1 (0.46) | FFAR4MEN1KMT2A | |
| SCHEMBL3891807 | 0.72 | KMT2A (0.47) | L3MBTL1USP2KMT2A | |
| SCHEMBL7013247 | 0.70 | L3MBTL1 (0.51) | TBXAS1ALOX15L3MBTL1TDP1MEN1 | |
| SCHEMBL3082606 | 0.70 | POLB (0.56) | L3MBTL1MEN1KMT2A | |
| SCHEMBL3897629 | 0.70 | KMT2A (0.49) | USP2PTGS2MEN1KMT2A | |
| SCHEMBL48684 | 0.70 | TDP1 (0.57) | FFAR4TDP1 | |
| SCHEMBL28430477 | 0.70 | MCL1 (0.60) | TBXAS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158121-A | Indolizine sPLA2Inhibitors | LILLY CO ELI (US) | 1997-08-27 | — | — | CN | disclosed |