Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL2643534 | 0.87 | MAPT (0.42) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5755261 | 0.83 | L3MBTL1 (0.39) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2643138 | 0.82 | ALDH1A1 (0.43) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7834274 | 0.82 | AKR1B1 (0.36) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7828783 | 0.81 | TP53 (0.41) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL2644088 | 0.76 | MEN1 (0.46) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2644119 | 0.73 | HTT (0.50) | L3MBTL1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL7304083 | 0.73 | L3MBTL1 (0.68) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2649499 | 0.72 | HCAR3 (0.51) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL7819742 | 0.69 | KDM4E (0.40) | L3MBTL1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1182427-A | Benzimidazole compounds and their use as modulators of GABA receptor complexes | NEUROSEARCH AS (DK) | 1998-05-20 | — | — | CN | disclosed |