Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | PLG | P00747 | 6/20 | 0.61 |
| ▸ | KLK1 | P06870 | 6/20 | 0.61 |
| ▸ | KLK6 | Q92876 | 6/20 | 0.61 |
| ▸ | FADS1 | O60427 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744848 | 0.88 | PTGS1 (0.75) | PTGS1FADS1KMT2AP2RX1NPC1 | |
| SCHEMBL27484183 | 0.86 | FADS1 (0.60) | KLKB1PTGS1PLGKLK1KLK6 | |
| SCHEMBL5853912 | 0.84 | FFAR1 (0.69) | PTGS1FADS1ABCB1ABCG2KMT2A | |
| SCHEMBL12700210 | 0.84 | ALDH1A1 (0.69) | KLKB1PLGKLK1KLK6KMT2A | |
| SCHEMBL30830441 | 0.83 | PTGS1 (0.69) | PTGS1FADS1KMT2AP2RX1NPC1 | |
| SCHEMBL2127535 | 0.83 | PTGS1 (0.69) | PTGS1FADS1KMT2AP2RX1NPC1 | |
| SCHEMBL1140055 | 0.83 | PTGS1 (0.68) | PTGS1FADS1KMT2AP2RX1NPC1 | |
| SCHEMBL7075705 | 0.83 | MEN1 (0.75) | KLKB1PLGKLK1KLK6KMT2A | |
| SCHEMBL4958043 | 0.82 | HPGD (0.63) | PTGS1FADS1ABCB1ABCG2KMT2A | |
| SCHEMBL27541341 | 0.82 | PTGS1 (0.56) | PTGS1FADS1ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101355946-B | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC | 2013-05-08 | — | — | CN | disclosed |
| CN-101355946-A | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |