Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 4/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | KLK1 | P06870 | 2/20 | 0.50 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483855 | 0.86 | KLKB1 (0.64) | FADS1PTGS1P2RX1PLGKLK1 | |
| SCHEMBL17744881 | 0.86 | FADS1 (0.72) | FADS1PTGS1P2RX1ALDH1A1KDM4E | |
| SCHEMBL17538569 | 0.85 | ALDH1A1 (0.63) | AURKBALDH1A1PLGKLK1KLK6 | |
| SCHEMBL14018734 | 0.85 | FADS1 (0.60) | FADS1PTGS1P2RX1ALDH1A1KDM4E | |
| SCHEMBL12264961 | 0.85 | FADS1 (0.60) | FADS1PTGS1AURKBP2RX1ALDH1A1 | |
| SCHEMBL23367948 | 0.84 | SMN1; SMN2 (0.68) | AURKBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27952999 | 0.84 | AURKB (0.56) | AURKBALDH1A1PLGKLK1KLK6 | |
| SCHEMBL20839480 | 0.83 | ITGB3 (0.60) | FADS1PTGS1P2RX1ALDH1A1 | |
| SCHEMBL27795055 | 0.83 | PLG (0.60) | AURKBPLGKLK1KLK6 | |
| SCHEMBL9810110 | 0.81 | ALDH1A1 (0.72) | FADS1PTGS1P2RX1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |