Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752913 | 0.80 | HTR6 (0.55) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL27555689 | 0.74 | ALDH1A1 (0.55) | PKMALDH1A1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL4731620 | 0.69 | AKR1C3 (0.65) | ALDH1A1MAPK1HTTKMT2APOLB | |
| SCHEMBL4675121 | 0.68 | PKM (0.45) | PKMALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL7938515 | 0.68 | KMT2A (0.79) | ALDH1A1SMN1; SMN2MAOBL3MBTL1TSHR | |
| SCHEMBL1366438 | 0.66 | PKM (1.00) | PKMALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL3794907 | 0.65 | PDE4D (0.53) | ALDH1A1MAOBKMT2AGAA | |
| SCHEMBL4093243 | 0.65 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2L3MBTL1LMNAHTT | |
| SCHEMBL7311044 | 0.64 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2L3MBTL1TSHRLMNA | |
| SCHEMBL4675478 | 0.64 | PKM (0.62) | PKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178913-C | Aromatic heterocycle compounds having HIV integrase inhibiting activities | ��Ұ����ҩ��ʽ���� | 2004-12-08 | — | — | CN | disclosed |
| CN-1335834-A | Aromatic heterocyclic compounds having HIV integrase inhibitory activity | SHIONOGI & CO (JP) | 2002-02-13 | — | — | CN | disclosed |