Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 15/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490461 | 0.82 | L3MBTL1 (0.31) | TRPM5L3MBTL1 | |
| SCHEMBL27474749 | 0.73 | CNR1 (0.46) | TRPM5CREBBPMCL1CNR2CNR1 | |
| SCHEMBL1223895 | 0.71 | CREBBP (0.57) | TRPM5CREBBPCNR1 | |
| Ethoxycarbonyl Group SCHEMBL27490855 | 0.71 | CREBBP (0.44) | TRPM5CREBBPL3MBTL1MCL1CNR1 | |
| SCHEMBL27474220 | 0.70 | MCL1 (0.43) | MCL1CNR2CNR1 | |
| SCHEMBL27487624 | 0.68 | HTR2A (0.36) | CNR2CNR1 | |
| SCHEMBL31689011 | 0.65 | CREBBP (0.49) | CREBBPL3MBTL1CNR2CNR1 | |
| SCHEMBL27528307 | 0.63 | P2RX7 (0.35) | CNR2CNR1 | |
| SCHEMBL13064359 | 0.63 | TRPM5 (0.47) | TRPM5CREBBPMCL1 | |
| SCHEMBL3596244 | 0.63 | LMNA (0.60) | TRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161334-A | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 1997-10-08 | — | — | CN | disclosed |