Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 11/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557284 | 0.87 | SLC6A4 (0.35) | SCN9ASLC6A4SLC6A3 | |
| SCHEMBL27511646 | 0.85 | SLC6A4 (0.35) | SCN9ASLC6A4SLC6A3 | |
| SCHEMBL27466734 | 0.70 | HDAC8 (0.38) | SLC6A4SLC6A3 | |
| SCHEMBL6173291 | 0.70 | SLC6A3 (0.39) | TACR1SLC6A4SLC6A3 | |
| SCHEMBL27466722 | 0.70 | HDAC8 (0.48) | — | |
| SCHEMBL27466733 | 0.70 | HDAC8 (0.38) | SLC6A4SLC6A3 | |
| SCHEMBL27482758 | 0.68 | MDM2 (0.41) | SLC6A3 | |
| SCHEMBL6174259 | 0.68 | SMURF1 (0.35) | TACR1 | |
| SCHEMBL6174270 | 0.68 | SMURF1 (0.35) | TACR1 | |
| SCHEMBL27466725 | 0.68 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209362-C | Tetrazolyl-phenyl acetamide glucokinase activators | HOFFMANN LA ROCHE (CH) | 2005-07-06 | — | — | CN | disclosed |
| CN-1466584-A | Tetrazolyl-phenyl acetamide glucokinase activators | - | 2004-01-07 | — | — | CN | disclosed |