Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27493349 | 0.84 | F2 (0.38) | HRH3HTR1AMLYCDKDM4EHTR2C | |
| SCHEMBL28741350 | 0.81 | ALDH1A1 (0.37) | HRH3KMT2AHPGDMLYCD | |
| SCHEMBL27532206 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AHPGDMLYCDMAPT | |
| SCHEMBL27494109 | 0.77 | DRD2 (0.36) | HRH3HPGDMLYCD | |
| SCHEMBL27495701 | 0.77 | DRD2 (0.40) | HTR1AHPGDMLYCD | |
| SCHEMBL27509546 | 0.76 | MLYCD (0.36) | MEN1KMT2AMLYCD | |
| SCHEMBL27492958 | 0.72 | HTR1A (0.44) | HTR1AMEN1KMT2ACYP3A4 | |
| SCHEMBL27493348 | 0.72 | HTR1A (0.44) | HTR1AMEN1KMT2ACYP3A4 | |
| SCHEMBL8303507 | 0.71 | HRH3 (0.65) | HRH3HTR1AOPRM1OPRK1 | |
| SCHEMBL29472508 | 0.69 | MLYCD (0.51) | MEN1KMT2AMLYCDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |