Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HAT1 | O14929 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | GUSB | P08236 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 4/20 | 0.33 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495701 | 0.94 | DRD2 (0.40) | DRD2DRD4DRD3GUSBALDH1A1 | |
| SCHEMBL28741350 | 0.91 | ALDH1A1 (0.37) | DRD2ALDH1A1HPGDADORA2AHRH3 | |
| SCHEMBL27532206 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDMLYCD | |
| SCHEMBL27492955 | 0.77 | HRH3 (0.37) | HPGDHRH3MLYCD | |
| SCHEMBL27510230 | 0.75 | THRB (0.40) | DRD2DRD4DRD3GUSBALDH1A1 | |
| SCHEMBL27492957 | 0.75 | ADRA1D (0.53) | DRD2 | |
| SCHEMBL8296056 | 0.74 | ADRA1D (0.48) | DRD2 | |
| SCHEMBL27563844 | 0.73 | HSD11B1 (0.39) | DRD2BCHEALDH1A1HPGD | |
| SCHEMBL27493349 | 0.72 | F2 (0.38) | ALDH1A1HRH3MLYCD | |
| SCHEMBL27495318 | 0.71 | GUSB (0.39) | DRD2DRD4DRD3HAT1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |