Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 7/20 | 0.35 |
| ▸ | MLYCD | O95822 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741350 | 0.93 | ALDH1A1 (0.37) | ALDH1A1HPGDMLYCDLMNAKMT2A | |
| SCHEMBL27495701 | 0.91 | DRD2 (0.40) | ALDH1A1HPGDMLYCDSLC6A4 | |
| SCHEMBL27563844 | 0.86 | HSD11B1 (0.39) | ALDH1A1HPGDHSD11B1MPOSLC6A4 | |
| SCHEMBL27494109 | 0.86 | DRD2 (0.36) | ALDH1A1HPGDMLYCD | |
| SCHEMBL27492955 | 0.81 | HRH3 (0.37) | HPGDMLYCDMEN1MAPTKMT2A | |
| SCHEMBL27493349 | 0.77 | F2 (0.38) | ALDH1A1MLYCDSLC6A4MAPT | |
| SCHEMBL27509546 | 0.72 | MLYCD (0.36) | MLYCDMEN1KMT2AL3MBTL1 | |
| SCHEMBL27495705 | 0.72 | HTR2A (0.45) | MPOSLC6A4TSHRKMT2A | |
| SCHEMBL27509165 | 0.71 | MPO (0.41) | ALDH1A1MPOTSHRMEN1MAPT | |
| SCHEMBL8299591 | 0.71 | OPRM1 (0.56) | HSD11B1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |