Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495316 | 0.93 | TDO2 (0.42) | LMNAALDH1A1GAAMAPTMMP1 | |
| SCHEMBL27494914 | 0.86 | MMP1 (0.40) | ALDH1A1GAAMAPTMMP1MMP2 | |
| SCHEMBL27494526 | 0.84 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTMPOMTNR1A | |
| SCHEMBL27509165 | 0.83 | MPO (0.41) | ALDH1A1MAPTMPOMTNR1AMTNR1B | |
| SCHEMBL27557415 | 0.81 | GAA (0.40) | ALDH1A1GAAMAPTMMP1MMP2 | |
| SCHEMBL27510950 | 0.77 | TDO2 (0.42) | LMNAALDH1A1MAPTKDR | |
| SCHEMBL27509893 | 0.76 | NPC1 (0.58) | ALDH1A1GAAMAPTCYP1A2HSD17B10 | |
| SCHEMBL28741340 | 0.76 | NPC1 (0.58) | ALDH1A1GAAMAPTCYP1A2HSD17B10 | |
| SCHEMBL27557417 | 0.76 | GAA (0.51) | ALDH1A1GAAMAPTCYP1A2HSD17B10 | |
| SCHEMBL27509166 | 0.76 | NPC1 (0.58) | ALDH1A1GAAMAPTCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |