Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 6/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510950 | 0.93 | TDO2 (0.42) | ALDH1A1LMNAMAPTTDO2ITGB3 | |
| SCHEMBL28741367 | 0.86 | GUSB (0.37) | ALDH1A1LMNA | |
| SCHEMBL27495706 | 0.84 | LMNA (0.42) | ALDH1A1LMNAMAPTMPOKDR | |
| SCHEMBL27509545 | 0.83 | MPO (0.38) | MAPTMPOHTR2AHTR2CMTNR1A | |
| SCHEMBL27524768 | 0.81 | GUSB (0.37) | ALDH1A1LMNAMAPTITGB3ITGAV | |
| SCHEMBL27510621 | 0.75 | ITGB3 (0.48) | ALDH1A1LMNAITGB3ITGAV | |
| SCHEMBL27492956 | 0.75 | DRD2 (0.42) | ALDH1A1ITGB3ITGAV | |
| SCHEMBL27494111 | 0.75 | DRD2 (0.42) | ALDH1A1ITGB3ITGAV | |
| SCHEMBL27495702 | 0.75 | DRD2 (0.42) | ALDH1A1ITGB3ITGAV | |
| SCHEMBL27511350 | 0.75 | TDO2 (0.37) | MAPTTDO2HTR2AHTR2CGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |