Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 11/20 | 0.52 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.44 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylbutazone SCHEMBL28843709 | 0.94 | ALDH1A1 (0.68) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| Oxyphenbutazone Anhydrous SCHEMBL28086649 | 0.89 | LMNA (0.77) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| SCHEMBL5279293 | 0.84 | CES2 (0.65) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| SCHEMBL6700291 | 0.80 | CES2 (0.63) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| SCHEMBL9380107 | 0.76 | CES2 (0.46) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| SCHEMBL9382481 | 0.75 | CES2 (0.60) | MAPTCES2 | |
| Phenylbutazone SCHEMBL8005041 | 0.73 | RAB9A (0.82) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| Phenylbutazone SCHEMBL3632 | 0.73 | RAB9A (0.82) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| Oxyphenbutazone Anhydrous SCHEMBL25857 | 0.72 | LMNA (1.00) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 | |
| Oxyphenbutazone Anhydrous SCHEMBL5316370 | 0.72 | LMNA (1.00) | ALDH1A1CYP3A4RAB9ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102143961-B | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2014-11-05 | — | — | CN | claimed |
| CN-102143961-A | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2011-08-03 | — | — | CN | claimed |
| CN-111479575-B | Compositions comprising a chemotherapeutic agent and a checkpoint inhibitor and methods of use | 北卡罗莱纳州立大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-116891540-A | Alginic acid derivatives with non-steroidal anti-inflammatory compounds attached thereto | 持田制药株式会社 | 2023-10-17 | — | — | CN | disclosed |
| CN-116059347-A | Treatment and prevention of cancer using HER3 antigen binding molecules | 蜂鸟生物科技私人有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114945363-A | Polyphosphazene drug carriers | 昂塞莱克斯制药公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-102292449-B | Prevent or treat thrombotic IL-6 antagonist | ALDER BIOPHARMACEUTICALS, INC. (US) | 2016-03-30 | — | — | CN | disclosed |
| CN-102143961-B | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2014-11-05 | — | — | CN | disclosed |
| CN-101316853-B | Benzothiazole and thiazolopyridine as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC | 2014-09-24 | — | — | CN | disclosed |
| CN-103145738-A | Imidazo [2,1-b] thiayole derivatives as SIRTUIN modulating compounds | SIRTRIS PHARMACEUTICALS INC | 2013-06-12 | — | — | CN | disclosed |
| CN-102292449-A | Antagonists of IL-6 to prevent or treat thrombosis | — | 2011-12-21 | — | — | CN | disclosed |
| CN-101277963-A | Benzimidazole derivatives as SIRTUIN modulators | SIRTIS PHARMACEUTICALS INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1898198-A | Alpha-hydroxy amides as bradykinin antagonists or inverse agonists | MERCK & CO INC (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1871215-A | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL MYERS SQUIBB CO (US) | 2006-11-29 | — | — | CN | disclosed |
| CN-1835944-A | Quinolyl amide derivatives as CCR-5 antagonists | SCHERING AG (DE) | 2006-09-20 | — | — | CN | disclosed |
| CN-1227248-C | Imidazolidine derivatives, their preparation, and their use as antinflamatory agent | AVENTIS PHARMA GMBH (DE) | 2005-11-16 | — | — | CN | disclosed |
| CN-1221535-C | Spiroimidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMA GMBH (DE) | 2005-10-05 | — | — | CN | disclosed |
| CN-1496360-A | Imidazolidine derivatives, their preparation, and their use as antinflamatory agent | ������ҽҩ�¹�����˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1433431-A | Interleukin-1 receptor antagonist-like molecules and uses thereof | AMGEN INC (US) | 2003-07-30 | — | — | CN | disclosed |
| CN-1356986-A | Spiroimidazolidine derivatives, their prepn. their use and pharmaceutical prepns. comprising them | AVENTIS PHARMA GMBH (DE) | 2002-07-03 | — | — | CN | disclosed |