Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545419 | 0.81 | DRD2 (0.76) | DRD2HTR2AHTR7KCNH2ACHE | |
| SCHEMBL1545162 | 0.81 | DRD2 (0.76) | DRD2HTR2AHTR7KCNH2ACHE | |
| SCHEMBL1545164 | 0.81 | DRD2 (0.76) | DRD2HTR2AHTR7KCNH2ACHE | |
| SCHEMBL8714677 | 0.80 | HTR2A (0.62) | DRD2HTR2AHTR1AADRA2AHTR2C | |
| SCHEMBL1544927 | 0.79 | HTR1A (0.80) | DRD2HTR2AHTR1AADRA2AHTR2C | |
| SCHEMBL22149696 | 0.79 | DRD2 (0.76) | DRD2HTR2AHTR1AHTR2CADRA1A | |
| SCHEMBL8523709 | 0.79 | HTR2A (0.62) | DRD2HTR2AHTR1AADRA2AHTR2C | |
| Methyl Alcohol SCHEMBL3645347 | 0.79 | DRD2 (0.61) | DRD2HTR2AHTR1AADRA2AHTR2C | |
| SCHEMBL1545151 | 0.79 | DRD2 (0.72) | DRD2HTR2AHTR1AADRA2AHTR2C | |
| SCHEMBL27523350 | 0.78 | HTR2A (0.65) | DRD2HTR2AHTR1AADRA2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086387-C | N- (aryloxyalkyl) heteroarylpiperidines and heteroarylpiperazines, their preparation and their use as pharmaceuticals | HOECHST MARION ROUSSEL INC (US) | 2002-06-19 | — | — | CN | disclosed |
| CN-1048037-A | N- (aryloxyalkyl) heteroarylpiperidines and heteroarylpiperazines, their preparation and their use as pharmaceuticals | HOECHST ROUSSEL PHARMA (US) | 1990-12-26 | — | — | CN | disclosed |