Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | CCKBR | P32239 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523709 | 0.90 | HTR2A (0.62) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| SCHEMBL1545461 | 0.81 | HTR1A (0.76) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| SCHEMBL7356978 | 0.81 | ACHE (0.71) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| Methyl Alcohol SCHEMBL3645347 | 0.81 | DRD2 (0.61) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| SCHEMBL9226934 | 0.80 | DRD2 (0.71) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| SCHEMBL27520101 | 0.80 | DRD2 (0.62) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| SCHEMBL5995122 | 0.80 | HTR1A (0.67) | HTR2ADRD2HTR1A | |
| Fumaric Acid SCHEMBL1545209 | 0.79 | ABCB11 (0.74) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| Fumaric Acid SCHEMBL1545268 | 0.79 | ABCB11 (0.74) | HTR2ADRD2HTR1AADRA2AHTR2C | |
| SCHEMBL8795133 | 0.79 | ACHE (0.71) | HTR2ADRD2HTR1AHTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776963-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-07 | — | — | US | disclosed |