Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569448 | 0.82 | DRD2 (0.45) | TNIKHDAC8KDM4EALDH1A1FPR2 | |
| SCHEMBL27485081 | 0.82 | PTGS1 (0.46) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL8560030 | 0.81 | TGM2 (0.46) | TNIKKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL16874550 | 0.80 | KCNH2 (0.51) | LMNA | |
| SCHEMBL8564264 | 0.79 | DDB1 (0.50) | HDAC1HDAC8HDAC6ALDH1A1L3MBTL1 | |
| SCHEMBL8564268 | 0.79 | DDB1 (0.50) | HDAC1HDAC8HDAC6ALDH1A1L3MBTL1 | |
| SCHEMBL1542776 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1 | |
| SCHEMBL8563968 | 0.78 | HDAC8 (0.40) | PKMHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL8564966 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HTTRAB9A | |
| SCHEMBL8564961 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1150950-A | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1997-06-04 | — | — | CN | disclosed |