Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569448 | 0.86 | DRD2 (0.45) | HDAC8ALDH1A1HDAC3NCOR2FPR2 | |
| Bromide SCHEMBL8899846 | 0.81 | PKM (0.41) | HDAC8PKMALDH1A1MAPTHDAC3 | |
| Bromide SCHEMBL8899853 | 0.81 | PKM (0.41) | HDAC8PKMALDH1A1MAPTHDAC3 | |
| SCHEMBL8561859 | 0.78 | SIRT2 (0.49) | HDAC8HDAC1HDAC6TP53 | |
| SCHEMBL27520459 | 0.78 | TNIK (0.46) | HDAC8PKMALDH1A1FPR2GAA | |
| SCHEMBL8563972 | 0.73 | TP53 (0.37) | HDAC1HDAC6TP53 | |
| SCHEMBL8560030 | 0.72 | TGM2 (0.46) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7617920 | 0.72 | PLA2G10 (0.46) | ALDH1A1FPR2 | |
| SCHEMBL7617915 | 0.72 | PLA2G10 (0.46) | ALDH1A1FPR2 | |
| SCHEMBL16874550 | 0.69 | KCNH2 (0.51) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |