Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537730 | 1.00 | CTSL (0.44) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL27562471 | 0.94 | CTSL (0.48) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL27559585 | 0.93 | LGMN (0.45) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL27562616 | 0.88 | CTSS (0.53) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL27559457 | 0.88 | CTSS (0.53) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL27559569 | 0.88 | SIRT1 (0.42) | SIRT2 | |
| SCHEMBL7378138 | 0.87 | CTSL (0.56) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7378143 | 0.87 | CTSL (0.56) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7171904 | 0.86 | PSMB5 (0.49) | CTSLCTSKCTSBCAPN1CAPN2 | |
| SCHEMBL9301339 | 0.85 | HTT (0.47) | CTSLCTSSCTSKCTSBSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1313863-A | Inhibitors of urokinase and angiogenesis | CORVAS INTERNAT INC (US) | 2001-09-19 | — | — | CN | disclosed |