Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15627517 | 0.94 | PSMB1 (0.48) | PSMB5PSMB1PSMB2CTSLCTSB | |
| Hydrochloric Acid SCHEMBL11145577 | 0.88 | PSMB1 (0.61) | PSMB5PSMB1PSMB2CTSLCTSB | |
| Hydrochloric Acid SCHEMBL11141841 | 0.87 | PSMB1 (0.61) | PSMB5PSMB1PSMB2CTSLCTSB | |
| SCHEMBL29434529 | 0.87 | NPY4R (0.53) | PSMB5PSMB1PSMB2CTSLCTSB | |
| SCHEMBL27537730 | 0.86 | CTSL (0.44) | PSMB1CTSLCTSBCAPN1CAPN2 | |
| SCHEMBL27537720 | 0.86 | CTSL (0.44) | PSMB1CTSLCTSBCAPN1CAPN2 | |
| SCHEMBL7264476 | 0.85 | CTSK (0.53) | PSMB5PSMB1PSMB2CTSLCTSB | |
| SCHEMBL7266455 | 0.85 | CTSK (0.53) | PSMB5PSMB1PSMB2CTSLCTSB | |
| SCHEMBL5980007 | 0.85 | CTSK (0.53) | PSMB5PSMB1PSMB2CTSLCTSB | |
| SCHEMBL11144460 | 0.85 | PSMB1 (0.58) | PSMB5PSMB1PSMB2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576613-B1 | Arginine derivatives; monitoring plasminogen activator levels; inhibiting angiogenesis and tumor cell growth | CORVAS INTERNATIONAL, INC. | 2003-06-10 | — | — | US | disclosed |
| US-6432922-B1 | ANTITUMOR AGENTS; ANGIOGENESIS INHIBITORS | CORVAS INTERNATIONAL, INC. | 2002-08-13 | — | — | US | disclosed |
| EP-1100814-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000005245-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2000-02-03 | — | — | WO | disclosed |