Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317736 | 0.82 | NPSR1 (0.49) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL27554772 | 0.82 | RAB9A (0.49) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7698761 | 0.81 | ALDH1A1 (0.51) | RAB9AKMT2AMAPK1NR4A2GAA | |
| SCHEMBL6315808 | 0.78 | GAA (0.74) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8658283 | 0.78 | L3MBTL1 (0.48) | NPC1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL7830099 | 0.76 | ALDH1A1 (0.47) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7834889 | 0.75 | MAPT (0.49) | RAB9ANPC1KMT2ASMN1; SMN2GAA | |
| SCHEMBL8657073 | 0.75 | ALOX5 (0.54) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8554616 | 0.74 | KIF11 (0.54) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7834393 | 0.74 | MAPT (0.54) | RAB9ANPC1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344270-A | Functionalized heterocycles as chemokine receptor modulators | THOUSAND YEARS MEDICAMENTS INC (US) | 2002-04-10 | — | — | CN | disclosed |