Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564358 | 0.84 | PTGS1 (0.43) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL27576872 | 0.81 | RAPGEF4 (0.53) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL27561517 | 0.80 | RAPGEF4 (0.33) | ALDH3A1KMT2AMEN1RAPGEF4 | |
| SCHEMBL27561385 | 0.80 | TDP1 (0.38) | MAPTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL27582103 | 0.80 | KDR (0.40) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL27582035 | 0.78 | P2RY4 (0.40) | KMT2AMAPTMEN1SMN1; SMN2TSHR | |
| SCHEMBL27561403 | 0.77 | PTGS1 (0.40) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL27561674 | 0.76 | AR (0.36) | KMT2AMAPTMEN1SMN1; SMN2TSHR | |
| SCHEMBL27561375 | 0.75 | CA2 (0.42) | TP53LMNA | |
| SCHEMBL18591632 | 0.72 | RAPGEF4 (0.48) | ALDH3A1KMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1351498-A | Pyrrolotriazines inhibitors of kinases | BRISTOL MYERS SQUIBB CO (US) | 2002-05-29 | — | — | CN | claimed |