Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646851 | 0.83 | AKR1C3 (0.42) | HDAC4ALDH1A1 | |
| SCHEMBL7063010 | 0.79 | RBP4 (0.38) | RBP4LIPETRPV1HDAC4HSP90AA1 | |
| SCHEMBL6817908 | 0.79 | NPC1 (0.33) | NPC1RAB9AALDH1A1 | |
| SCHEMBL6921386 | 0.65 | RAB9A (0.34) | TRPV1GRM5NPC1RAB9A | |
| SCHEMBL6817904 | 0.64 | NPC1 (0.32) | NPC1RAB9AALDH1A1 | |
| SCHEMBL7619039 | 0.62 | GRM5 (0.36) | HSP90AA1HSP90AB1GRM5NPC1RAB9A | |
| SCHEMBL6568437 | 0.61 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL24746289 | 0.60 | HSD11B1 (0.52) | HSP90AA1HSP90AB1GRM5MEN1ALDH1A1 | |
| SCHEMBL5536446 | 0.60 | GAA (0.71) | TRPV1HSP90AA1HSP90AB1GRM5MEN1 | |
| SCHEMBL7920913 | 0.60 | HTT (0.38) | LIPEHSP90AA1HSP90AB1GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |