Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A1 | P53007 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422318 | 0.82 | SLC25A1 (0.66) | SLC25A1MEN1KMT2ANPC1IDH1 | |
| SCHEMBL30252330 | 0.81 | SLC25A1 (1.00) | SLC25A1MEN1KMT2ANPC1POLB | |
| SCHEMBL17329296 | 0.81 | SLC25A1 (1.00) | SLC25A1MEN1KMT2ANPC1POLB | |
| SCHEMBL893934 | 0.80 | CA2 (0.71) | SLC25A1MEN1KMT2APOLBCA12 | |
| SCHEMBL16431026 | 0.78 | PGR (0.64) | SLC25A1MEN1KMT2APOLBCA2 | |
| SCHEMBL27579266 | 0.77 | CA12 (0.51) | SLC25A1MEN1KMT2AL3MBTL1CA12 | |
| SCHEMBL11137629 | 0.77 | MEN1 (0.59) | SLC25A1MEN1KMT2AIDH1POLB | |
| SCHEMBL22980417 | 0.77 | MCL1 (0.45) | SLC25A1MEN1KMT2ANPC1SLC22A12 | |
| SCHEMBL3769126 | 0.77 | PGR (0.73) | MEN1KMT2ASLC22A12MAPTALDH1A1 | |
| SCHEMBL30737482 | 0.77 | MEN1 (0.65) | MEN1KMT2ASLC22A12POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |