Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565350 | 0.85 | MAPK1 (0.51) | HCAR2MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL27568452 | 0.83 | FTO (0.42) | ATMMAPK1MEN1MAPTKMT2A | |
| SCHEMBL27585150 | 0.81 | MAPK1 (0.52) | MAPK1KMT2AALDH1A1GAAHTT | |
| SCHEMBL27341171 | 0.79 | PKN1 (0.52) | ATMCYP46A1MEN1MAPTKMT2A | |
| SCHEMBL29094948 | 0.78 | FABP4 (0.54) | ATMMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL27565328 | 0.77 | KDM4E (0.43) | MEN1MAPTKMT2AALDH1A1TSHR | |
| SCHEMBL27585176 | 0.75 | MAP4K4 (0.48) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL27532005 | 0.73 | HCAR2 (0.44) | HCAR2XDHSLC22A12ALDH1A1HTT | |
| SCHEMBL27585156 | 0.73 | LMNA (0.48) | MAPK1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL27565347 | 0.73 | SLC6A3 (0.43) | MAPK1MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | claimed |
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | disclosed |