Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767668 | 0.87 | PGR (0.36) | GLAESR1PGRCHRM2ADORA3 | |
| SCHEMBL16767670 | 0.87 | PGR (0.36) | GLAESR1PGRCHRM2ADORA3 | |
| SCHEMBL6257126 | 0.82 | — | — | |
| SCHEMBL3192528 | 0.81 | — | — | |
| SCHEMBL30889158 | 0.80 | — | — | |
| SCHEMBL30889145 | 0.80 | MEN1 (0.32) | — | |
| SCHEMBL30889140 | 0.80 | — | — | |
| SCHEMBL28146878 | 0.79 | HIF1A (0.36) | ESR1ALDH1A1 | |
| SCHEMBL11902289 | 0.79 | ELANE (0.39) | — | |
| SCHEMBL20421273 | 0.78 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556750-B1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME | LG CHEMICAL LTD (KR) | 2021-02-24 | — | — | EP | disclosed |
| US-8927750-B2 | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules | UNIVERSITAET ZU KOELN (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8927750-B2 | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules | UNIVERSITAET ZU KOELN (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8927750-B2 | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules | UNIVERSITAET ZU KOELN (DE) | 2015-01-06 | — | — | US | disclosed |
| US-20120202774-A1 | ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES | UNIVERSITAET REGENSBURG (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120202774-A1 | ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES | UNIVERSITAET REGENSBURG (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120202774-A1 | ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES | UNIVERSITAET REGENSBURG (DE) | 2012-08-09 | — | — | US | disclosed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-11-05 | — | — | US | disclosed |
| US-4794193-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4709707-A | Use of 4,4A,5,6-tetrahydro-7-methyl-2-(3H) naphthalenone in augmenting or enhancing the aroma or taste of smoking tobacco and smoking tobacco articles | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1987-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | GLA 828/4885LMNA 216/4885ESR1 2623/4885 |
| US-20120202774-A1 | ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES | PPOX, APEH, ACOX3 | GLA 1714/4885LMNA 4172/4885ESR1 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.