Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 7/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480569 | 0.82 | CYP2C19 (0.61) | CYP2C19CYP2C9EYA3L3MBTL1POLB | |
| SCHEMBL8994709 | 0.79 | CYP2C19 (1.00) | CYP2C19CYP2C9EYA3L3MBTL1SMN1; SMN2 | |
| SCHEMBL6490125 | 0.78 | EYA3 (0.69) | CYP2C19CYP2C9EYA3POLBTHRA | |
| SCHEMBL6482824 | 0.73 | THRA (0.72) | CYP2C19CYP2C9EYA3POLBTHRA | |
| SCHEMBL1755970 | 0.72 | ACSL1 (0.53) | CYP2C19EYA3L3MBTL1THRATHRB | |
| SCHEMBL28245008 | 0.72 | CYP2C19 (0.79) | CYP2C19CYP2C9EYA3L3MBTL1THRA | |
| SCHEMBL18018241 | 0.70 | CYP2C19 (0.61) | CYP2C19CYP2C9EYA3L3MBTL1POLB | |
| SCHEMBL9316490 | 0.70 | CYP2C19 (0.73) | CYP2C19CYP2C9EYA3L3MBTL1THRA | |
| SCHEMBL30753455 | 0.70 | CYP2C19 (0.54) | CYP2C19CYP2C9EYA3L3MBTL1POLB | |
| SCHEMBL28245012 | 0.69 | CYP2C19 (0.79) | CYP2C19CYP2C9EYA3L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1533274-A | Benzofuranes and their use in treatment of artrial fibrillation | �����ɷ� | 2004-09-29 | — | — | CN | disclosed |