SCHEMBL6490125

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6480569	0.86	CYP2C19 (0.61)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL6737999	0.83	EYA3 (0.71)	EYA3CYP2C19CYP2C9GABRA1GABRB1
	SCHEMBL6574630	0.82	GABRA1 (0.51)	EYA3CYP2C19CYP2C9GABRA1GABRB1
	SCHEMBL3219908	0.82	EYA3 (1.00)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL6482824	0.81	THRA (0.72)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL27586552	0.78	CYP2C19 (0.64)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL28245008	0.78	CYP2C19 (0.79)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL8994710	0.77	CYP2C19 (1.00)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL28245012	0.75	CYP2C19 (0.79)	EYA3CYP2C19CYP2C9THRBTHRA
	SCHEMBL6482244	0.73	THRA (0.51)	EYA3CYP2C19CYP2C9THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.