Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110420 | 0.81 | ALDH1A1 (0.52) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL27587711 | 0.79 | GPR35 (0.51) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL9626541 | 0.77 | ITGA4 (0.47) | ALDH1A1GAAMAPTLMNAKMT2A | |
| SCHEMBL7918653 | 0.75 | CYP3A4 (0.47) | ALDH1A1GAAHTTTSHRSMN1; SMN2 | |
| SCHEMBL27605699 | 0.74 | GPR35 (0.46) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL27587814 | 0.73 | GPR35 (0.45) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL27587702 | 0.72 | MGLL (0.45) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL27605676 | 0.71 | ALDH1A1 (0.43) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL27587720 | 0.71 | GPR35 (0.43) | ALDH1A1GPR35L3MBTL1GAATHRB | |
| SCHEMBL27562642 | 0.71 | ALDH1A1 (0.47) | ALDH1A1GPR35GAATHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |