Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915293 | 0.78 | SMN1; SMN2 (0.39) | CYP3A4SMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL27587729 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KMT2APOLBHTT | |
| SCHEMBL11570711 | 0.73 | CYP3A4 (0.50) | CYP3A4SMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL848208 | 0.72 | TSHR (0.36) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL692306 | 0.71 | ALDH1A1 (0.48) | CYP3A4ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6934889 | 0.71 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL16278131 | 0.69 | MLYCD (0.34) | CYP3A4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27799342 | 0.69 | MMP14 (0.50) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL1990599 | 0.68 | ADRA2C (0.50) | CYP3A4SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL27947424 | 0.67 | SMN1; SMN2 (0.50) | CYP3A4SMN1; SMN2ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200831-B1 | HEAT-CURING A COATING OF A POLYAMIC ACID BASED ON A TETRACARBOXYLIC ACID AND A DIAMINE CONTAINNG AN ACTIVE OXYGEN OR NITROGEN FUNCTIONAL GROUP; SEALING THE EXTERNAL TERMINALS WITH A RESIN, E.G. AN EPOXIDE | HITACHI, LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6087006-A | SEMICONDUCTOR DEVICE HAVING SURFACE-PROTECTING FILM COMPRISING POLYIMIDE OBTAINED BY HEAT-CURING PRECURSOR HAVING POLAR SUBSTITUENTS AS THE SIDE CHAINS | HITACHI, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |