Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587826 | 0.89 | MAPT (0.46) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL27605699 | 0.83 | GPR35 (0.46) | MAPTATML3MBTL1MEN1KMT2A | |
| SCHEMBL27587714 | 0.83 | SMN1; SMN2 (0.47) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL27587711 | 0.81 | GPR35 (0.51) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL3018832 | 0.81 | MAPT (0.48) | NPC1MAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL27587720 | 0.80 | GPR35 (0.43) | NPC1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL27587702 | 0.79 | MGLL (0.45) | MAPTATML3MBTL1MEN1KMT2A | |
| SCHEMBL9488095 | 0.78 | PTGS2 (0.41) | MAPTRAB9AL3MBTL1ALDH1A1GAA | |
| SCHEMBL11198518 | 0.77 | LMNA (0.61) | NPC1MAPTKDM4ERAB9AL3MBTL1 | |
| SCHEMBL6824083 | 0.77 | L3MBTL1 (0.42) | NPC1MAPTKDM4ERAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |