Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570113 | 0.83 | DRD2 (0.45) | DRD2DRD3DRD4HTR7KCNH2 | |
| SCHEMBL6597607 | 0.80 | HTR7 (0.49) | DRD2DRD3DRD4HTR7KCNH2 | |
| SCHEMBL27588796 | 0.79 | ACHE (0.38) | DRD2DRD3DRD4HTR7 | |
| SCHEMBL7088347 | 0.77 | DRD2 (0.41) | DRD2DRD3DRD4HTR7KCNH2 | |
| SCHEMBL6599041 | 0.62 | HTR7 (0.69) | DRD2DRD3DRD4HTR7KCNH2 | |
| SCHEMBL7502808 | 0.61 | ALDH1A1 (0.33) | — | |
| SCHEMBL22371883 | 0.59 | HEXA (0.44) | — | |
| SCHEMBL6580508 | 0.59 | DRD3 (0.60) | DRD2DRD3DRD4HTR7CHRM1 | |
| SCHEMBL3340549 | 0.59 | LTA4H (0.48) | HTR7 | |
| SCHEMBL4309899 | 0.58 | HTR7 (0.53) | DRD2DRD3DRD4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1446216-A | Indole derivatives for the treatment of CNS disorders | LUNDEBECK AS H (DK) | 2003-10-01 | — | — | CN | claimed |
| CN-1446216-A | Indole derivatives for the treatment of CNS disorders | LUNDEBECK AS H (DK) | 2003-10-01 | — | — | CN | disclosed |