Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913465 | 0.90 | NPC1 (0.47) | SMN1; SMN2RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL2943035 | 0.87 | MEN1 (0.43) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL27597975 | 0.84 | BDKRB2 (0.37) | SMN1; SMN2RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL27616653 | 0.83 | PKM (0.43) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2947678 | 0.75 | KDM4E (0.39) | RAB9AMAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2914481 | 0.75 | LMNA (0.45) | SMN1; SMN2RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL2910858 | 0.73 | MEN1 (0.45) | SMN1; SMN2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2913757 | 0.71 | RAB9A (0.47) | SMN1; SMN2RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL2911504 | 0.71 | KDM4E (0.42) | RAB9AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL2905201 | 0.71 | LMNA (0.36) | SMN1; SMN2RAB9AMAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1638763-A | antidepressants | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-07-13 | — | — | CN | disclosed |