SCHEMBL2760099

SCHEMBL2760099

C=C(F)C(=O)CC(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.38
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14556955 0.71 TET2 (0.63) TET2MEN1KMT2AHTTNPSR1
SCHEMBL2947382 0.71 KMT2A (0.39) TET2MEN1KMT2AHTTNPSR1
SCHEMBL11913512 0.71 TET2 (0.34) TET2MEN1KMT2AHTTNPSR1
SCHEMBL960819 0.69 ACLY (0.48) TET2MEN1KMT2AHTTNPSR1
SCHEMBL13560384 0.67 KMT2A (0.41) TET2MEN1KMT2AHTTNPSR1
SCHEMBL2962912 0.67 MEN1 (0.33) TET2MEN1KMT2AHTTNPSR1
SCHEMBL5605062 0.67 KMT2A (0.41) TET2MEN1KMT2AHTTNPSR1
SCHEMBL2760102 0.67 ALDH1A1 (0.39) TET2MEN1KMT2AHTTNPSR1
SCHEMBL24600152 0.66
SCHEMBL8391629 0.66 ALDH1A1 (0.38) TET2MEN1KMT2AHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
US-8623589-B2 Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-01-07 US disclosed
US-8623589-B2 Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-01-07 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-8455176-B2 Coating composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-06-04 US disclosed
WO-2012168785-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-13 WO disclosed
US-20120308939-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-06 US disclosed
US-20120308939-A1 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-06 US disclosed
US-20120122029-A1 Underlayer Developable Coating Compositions and Processes Thereof AZ ELECTRONIC MATERIALS USA CORP. 2012-05-17 US disclosed
US-20120122029-A1 Underlayer Developable Coating Compositions and Processes Thereof AZ ELECTRONIC MATERIALS USA CORP. 2012-05-17 US disclosed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119972-A1 COATING COMPOSITION MERCK PATENT GMBH (DE) 2010-05-13 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 TET2 104/4885MEN1 883/4885KMT2A 1852/4885
US-20100119972-A1 COATING COMPOSITION S100A9, CAPG, C5 TET2 225/4885MEN1 1222/4885KMT2A 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.