Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631464 | 0.77 | IGF1R (0.56) | DCPSDHFR | |
| SCHEMBL27631996 | 0.76 | DCPS (0.48) | DCPSDHFR | |
| SCHEMBL656838 | 0.75 | MRGPRX4 (0.50) | CTSSS1PR1MRGPRX4 | |
| SCHEMBL27631545 | 0.74 | MPL (0.45) | — | |
| SCHEMBL27631479 | 0.73 | KIF11 (0.53) | — | |
| SCHEMBL10429320 | 0.73 | S1PR1 (0.47) | CTSSS1PR1MRGPRX4S1PR4S1PR3 | |
| SCHEMBL21928805 | 0.72 | CTSS (0.43) | CTSSS1PR1MRGPRX4S1PR4S1PR3 | |
| SCHEMBL20756090 | 0.71 | RXRA (0.54) | CTSSMRGPRX4 | |
| SCHEMBL79415 | 0.71 | RXRA (0.52) | CTSSS1PR1MRGPRX4 | |
| SCHEMBL2970971 | 0.70 | MRGPRX4 (0.45) | CTSSMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |