Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MDH2 | P40926 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27613153 | 0.94 | ALDH1A1 (0.40) | ALDH1A1HPGDMDH2SMN1; SMN2PTPN1 | |
| Tert-Butyl Formate SCHEMBL28771408 | 0.90 | ACHE (0.39) | MEN1LTA4HPLA2G2AKMT2AHSP90AA1 | |
| Tert-Butyl Formate SCHEMBL27613194 | 0.85 | LTA4H (0.41) | MEN1LTA4HPLA2G2AKMT2AHSP90AA1 | |
| Tert-Butyl Formate SCHEMBL27613146 | 0.84 | ALDH1A1 (0.40) | ACHECYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL5337035 | 0.81 | GHSR (0.34) | — | |
| SCHEMBL5347008 | 0.79 | GHSR (0.33) | ACHEPOLB | |
| Tert-Butyl Formate SCHEMBL28757223 | 0.79 | MDH2 (0.45) | MEN1LTA4HPLA2G2AKMT2AHSP90AA1 | |
| Tert-Butyl Formate SCHEMBL27632220 | 0.74 | SIRT2 (0.55) | PTPN1 | |
| Tert-Butyl Formate SCHEMBL27613248 | 0.73 | ACHE (0.43) | MEN1LTA4HPLA2G2AKMT2AHSP90AA1 | |
| SCHEMBL7822743 | 0.71 | CAMK2D (0.44) | MEN1LTA4HPLA2G2AKMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100412076-C | Novel substituted [1,4] benzodioxino [2, 3-e ] isoindole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2008-08-20 | — | — | CN | disclosed |
| CN-1705672-A | New benzodioxino-isoindole derivatives, useful for treatment of cancer, are inhibitors of cell cycle | SERVIER LAB (FR) | 2005-12-07 | — | — | CN | disclosed |