Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502853 | 0.72 | KCNMA1 (0.67) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL23762162 | 0.72 | SLC9A1 (0.49) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL21668428 | 0.69 | KCNMA1 (0.47) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL16856689 | 0.68 | KCNMA1 (0.48) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL21512532 | 0.67 | KCNMA1 (0.50) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL12202907 | 0.67 | SMN1; SMN2 (0.41) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL15426146 | 0.66 | PKM (0.55) | KCNMA1TDP1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL11343969 | 0.66 | ADORA3 (0.39) | KCNMA1SLC9A1TSHRSMN1; SMN2CASP3 | |
| SCHEMBL18599169 | 0.66 | KCNMA1 (0.55) | KCNMA1SLC9A1TSHRSMN1; SMN2RAB9A | |
| SCHEMBL23840194 | 0.65 | KCNMA1 (0.64) | KCNMA1SLC9A1TDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639112-A | Substituted amides having cannabinoid-1 receptor activity | MERCK & CO INC (US) | 2005-07-13 | — | — | CN | disclosed |