Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiouracil SCHEMBL4958659 | 0.82 | TP53 (0.66) | TP53MMP2ATAD2CRBNUBE2N | |
| Thiouracil SCHEMBL18815516 | 0.76 | TP53 (0.76) | TP53MMP2CRBN | |
| Thymine SCHEMBL5007601 | 0.75 | ATAD2 (0.68) | TP53MMP2ATAD2CRBN | |
| Thymine SCHEMBL17144680 | 0.75 | ATAD2 (0.54) | TP53MMP2ATAD2CRBN | |
| Pyrimidine SCHEMBL29014623 | 0.74 | ATAD2 (0.46) | ATAD2UBE2NKDM3BHDAC8 | |
| Thymine SCHEMBL29281739 | 0.73 | ATAD2 (0.70) | ATAD2 | |
| Uracil SCHEMBL7977993 | 0.73 | CRBN (0.68) | TP53MMP2CRBN | |
| Uracil SCHEMBL27698159 | 0.72 | CRBN (0.65) | TP53MMP2CRBN | |
| Thymine SCHEMBL574783 | 0.70 | ATAD2 (0.70) | TP53MMP2ATAD2CRBN | |
| Thymine SCHEMBL29232704 | 0.70 | ATAD2 (0.76) | MMP2ATAD2UBE2NKDM3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1715413-A | Corynebacterium glutamicum genes encoding metabolic pathway proteins | BASF AG (DE) | 2006-01-04 | — | — | CN | disclosed |