Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | CFTR | P13569 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671882 | 0.81 | MEN1 (0.82) | MEN1KMT2AALDH1A1MAPTCFTR | |
| SCHEMBL17309311 | 0.81 | CA9 (0.74) | ALDH1A1MAPTLMNAMAPK1CA9 | |
| SCHEMBL19481509 | 0.81 | CA9 (0.74) | ALDH1A1MAPTLMNAMAPK1CA9 | |
| SCHEMBL29462301 | 0.81 | MEN1 (1.00) | MEN1KMT2AALDH1A1MAPTCFTR | |
| SCHEMBL13727246 | 0.80 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL18857854 | 0.80 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL13727245 | 0.80 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL3364187 | 0.77 | CFTR (1.00) | MEN1KMT2AALDH1A1MAPTCFTR | |
| SCHEMBL3364192 | 0.77 | CFTR (1.00) | MEN1KMT2AALDH1A1MAPTCFTR | |
| SCHEMBL10668045 | 0.73 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1MAPTCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1657529-A | 2-substituted imine thia zlidine derivative its preparation technology and medicinal composition | SHANGHAI INST PHARM INDUSTRY (CN) | 2005-08-24 | — | — | CN | disclosed |